Prednisolone-21-stearoylglycolate in scleritis.

Prednisolone-21-stearoylglycolate in scleritis.

Plasma prednisolone levels and adrenocortical responsiveness after administration of prednisolone-21-phosphate as a retention enema.

Plasma prednisolone levels have been measured by radioimmunoassay after oral and rectal administration to healthy volunteers and to patients with idiopathic proctocolitis. The amount of prednisolone absorbed from a 20 mg retention enema given to patients with proctocolitis was about 44% of that absorbed from the same dose orally administered. Adrenocortical response to synthetic ACTH in patient...

Double-blind trial of the treatment of episcleritis-scleritis with oxyphenbutazone or prednisolone.

THE clinical impression of one of us (D.W.S.) that oxyphenbutazone (Tanderil) had a markedly beneficial effect on episcleritis gained some confirmation by the short report of Bannerjee and Taylor (1961). It was therefore decided to carry out a controlled double-blind trial. The object of this trial was to assess the comparative value of oxyphenbutazone as an alternative to prednisolone in the t...

Orbital myositis in scleritis.

AIMS To investigate the association between scleritis and myositis. METHODS Retrospective, non-comparative case series. Records and ultrasonograms were examined of 132 patients, with a diagnosis of episcleritis or scleritis, who attended the ophthalmology department at Leiden University Medical Center between 1997 and 2000. 103 were eligible for comprehensive examination. Medical records were...

Tubercular scleritis.

Scleritis is a severe painful inflammatory process centred in the sclera. A scleritis may be a harbinger of many systemic diseases so that it is important to exclude multisystem disease. We describe a case of unilateral tubercular anterior nodular non-necrotizing scleritis. Anterior nodular non-necrotizing scleritis is relatively an uncommon manifestation of tuberculosis. It may be difficult to...